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所在位置:所有产品 > 抗体抗原 > 一抗 > IRF3抗体
IRF3抗体图片
产品货号:
Z37416
中文名称:
IRF3抗体
英文名称:
Anti-IRF3 Antibody (Clone#11H2)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-IRF3 Antibody (Clone#11H2)
指标别名interferon regulatory factor 3;IRF 3;IRF3
克隆性Monoclonal
检验物种mouse,rat
应用范围WB,ICC/IF,FCM
基因名称Irf3
克隆号11H2
抗体来源Mouse
抗体类型IgG1
免疫原E.coli-derived mouse IRF3 recombinant protein (Position:M1-I419).
实际分子量50~55KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料IRF3(interferon regulatory factor 3) is a member of the interferon regulatory transcription factor (IRF) family.The IRF3 gene is mapped on 19q13.33.IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP.IRF3 plays an important role in the innate immune system's response to viral infection.Aggregated MAVS have been found to activate IRF3 dimerization.Although IRF3 increased transcriptional activity from an ISRE-containing promoter,expression of IRF3 as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase (CAT) reporter gene containing repeats of the Gal4-binding sites.Translocation of IRF3 was accompanied by an increase in serine and threonine phosphorylation.The transcriptional activators CREBBP and EP300 coimmunoprecipitated with IRF3 only subsequent to viral infection,and the authors stated that these are also subunits of DRAF1.
Uniprot IDP70671
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for ICC.
基因名全称interferon regulatory factor 3
蛋白名全称Interferon regulatory factor 3
推荐稀释比
Western blot(WB) 1:500~2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells

相关搜索:IRF3抗体IRF3单抗Anti-IRF3 Antibody (Clone#11H2)
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